Phase II/III data from a trial of Italian drugmaker Cosmo Pharmaceuticals' broad-spectrum antibiotic Rifamycin MMX (CB-01-11) indicate that the drug is effective in combating infectious diarrhea. The firm said that its MMX delivery technology allows the product, in the form of an oral tablet, to transit unabsorbed into the colon-bypassing beneficial bacteria in the small intestine.
Reformulation of topical antibiotic
Rifamycin MMX is a reformulated version of the broad-spectrum antibiotic rifamycin, which is approved for parenteral and topical use in a range of medications. In common with all antibiotics of this type, Cosmo's product inhibits DNA-dependent RNA synthesis via a high-affinity interaction with bacterial RNA polymerase.
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