Roche/Genentech license GlycArt's GA101
Genentech has licensed a Phase I/II-stage drug candidate from GlycArt, a firm wholly-owned by Genentech's parent company, Swiss drug major Roche.
GA101 is a humanized anti-CD20 monoclonal antibody engineered to increase both direct- and immune-mediated target cell death, for the potential treatment of hematological malignancies and other oncology-related B-cell disorders such as non-Hodgkin's lymphoma.
Pablo Umana, chief scientific officer of Switzerland-based GlycArt, said: "with its unique mode of action, we believe GA101 has the potential to extend the therapeutic benefit over current standards of care, including treatment for patients who do not respond to current therapies."
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