Roche partners with OBT on novel immuno-oncology targets

19 March 2025

UK biotech Oxford BioTherapeutics (OBT), a clinical stage oncology company with a pipeline of immuno-oncology (I-O) and antibody drug conjugate (ADC)-based therapies, today announced a multi-year collaboration with Swiss pharma giant Roche (ROG: SIX) to discover novel potentially first-in-class antibody-based therapeutics for the treatment of cancer.

OBT, which also has a base in San Jose in the USA, recently launched enhanced proprietary OGAP-Verify discovery platform enables greater sensitivity and thereby the selection of targets with improved attributes for drug development.

The deal provides OBT with up to $36 million upfront payments from Roche and eligibility for milestone payments potentially exceeding $1 billion, plus product royalties on net sales.  Under the terms of the agreement, targets are identified via the OGAP-Verify discovery platform and will be validated through the research collaboration.

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