Roche's Tamiflu ineffective against primary flu strain for this season; GSK's Relenza set to take over

12 January 2009

Swiss drug major Roche's gold-standard flu medicine Tamiflu (oseltamivir) is ineffective against the main type of influenza set to  affect the USA this season, says Centers for Disease Control and  Prevention (CDC).

From October 1 to December 13, 2008, the CDC tested 50 H1N1 influenza A  strains, eight H3N2, and 20 influenza B viruses from 15 US states for  resistance to two groups of antiviral drugs: neuraminidase inhibitors,  such as Tamiflu, and adamantanes. The H1N1 strain was found to be  resistant to the Roche drug in 49, or 98%, of the samples tested.

CDC says still too early to predict which strain will be prevalent

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