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The Pharma Letter M&A roundup - November 2025
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Merck & Co and Johnson & Johnson were pharma's big buyers in M&A during November.   2 December 2025


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On December 12, 2025, the US Food and Drug Administration approved Johnson & Johnson subsidiary Janssen Biotech’s Akeega (niraparib and abiraterone acetate with prednisone for adults with deleterious or suspected deleterious BRCA2-mutated (BRCA2m) metastatic castration-sensitive prostate cancer (mCSPC), as determined by an FDA-approved test.   15 December 2025

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M&A news last week featured Mirum Pharmaceuticals announcing plans to acquire fellow USA-based Bluejay Therapeutics and its kidney disease candidate brelovitug. The US Advisory Committee on Immunization Practices (ACIP) revealed changes to guidance on hepatitis B vaccination for newborns. On the research front, Swiss pharma giant Roche presented strong new data on its giredestrant in early breast cancer, while Rezolute released disappointing Phase III data on its congenital hyperinsulinism candidate ersodetug.   14 December 2025

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