US firms Sigma-Aldrich and Sangamo BioSciences have entered a research and license agreement to provide Swiss drug major Roche with non-exclusive, worldwide rights for the use of proprietary zinc finger nuclease (ZFN) technology to develop cell-lines and transgenic animals that have targeted modifications in a specified gene in a specified species. Roche also has an option to obtain an exclusive, global license for the commercial use of such ZFN-generated transgenic animals in the production of therapeutic and diagnostic products.
The research phase of the agreement will be conducted in collaboration with both Sangamo and Sigma-Aldrich, the former's exclusive licensee of ZFN technology for high-value research reagents.
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