Japanese drugmaker Santen Pharmaceutical has licensed glaucoma drug tafluprost to US drug major Merck & Co. A preserved and preservative-free formulation of the prostaglandin analog has received marketing approval for the reduction of elevated intraocular pressure in open-angle glaucoma and ocular hypertension in several European and Nordic countries, as well as Japan, and has been filed for approval in additional European and Asia-Pacific markets. Under the terms of the license deal, Merck will pay an undisclosed fee as well as milestones and royalties for both preserved and preservative-free formulations of tafluprost in exchange for exclusive commercial rights in western Europe (excluding Germany), North America, South America and Africa. Merck will provide promotion support to Santen in Germany and Poland. If the agent is approved in the USA, the Japanese firm has an option to co-promote it there.
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