Scientists find removable block to gene therapy

21 May 2009

The charity Cancer Research UK's scientists have discovered that an overactive cancer gene can block the delivery of gene therapy to the  cell nucleus, according to research published in the Journal of Clinical  Investigation.

By blocking the gene CEACAM6, the researchers found that gene therapy  was better able to gain access to the nucleus of affected cells, and so  increase the survival rate of cancer-carrying mice treated with an  anticancer adenovirus.

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