Sepracor's Norastemizole "Effective" In Phase II
- Sepracor's nonsedating antihistamine norastemizole has provedeffective in a Phase II study, and the company now plans to push on with a pivotal Phase II/III trial starting this month. The drug is an active metabolite of astemizole, marketed by Johnson & Johnson as Hismanal, and offers improved efficacy and tolerability. Meantime, the company has filed a New Drug Application in the USA for a single-isomer formulation of albuterol (levalbuterol), another drug in its portfolio of "Improved Chemical Entities."
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