A study published in the Journal of Neuroscience supports Australia-based Prana Biotechnology's strategy for treating Alzheimer's disease, according to the firm.
University of California, USA, researchers found that the release of zinc from synapses is critical for the Abeta protein to form oligomers and to aggregate, causing AD. Prana's candidate PBT2 targets a toxic form of Abeta by inhibiting its reaction with zinc.
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