Danish biotechnology company TopoTarget AS says it has been granted a key US patent relating to the use of valproic acid in the treatment of cancer. The patent, number 7,265,154, is valid until February 2022, and covers use of the agent and close derivatives, in all major types of cancer.
Company chief executive Peter Jensen said that the patent provides the firm with a strong position for its Baceca, Avugane and Savicol products, which are in Phase II development for various indications including skin diseases and familial adenomatous polyposis. Prof Jensen added that "clinical data we have collected to now supports our belief that there is a clear opportunity in repurposing VPA in order to help patients with different types of skin cancer including basal cell carcinoma where we recently published positive Phase II data."
European HDAC patent
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