Data presented at the American College of Cardiology annual meeting in Florida, show that US health care major Abbott Laboratories' Trilipix (fenofibric acid) delayed-release capsules plus AstraZeneca's Crestor (rosuvastatin) met all of the study's primary endpoints. Trilipix 135mg plus Crestor 5mg significantly improved high-density lipoprotein cholesterol and triglycerides versus Crestor 5mg alone and significantly improved LDL cholesterol compared to Trilipix 135mg alone in patients with lipid problems.
"More comprehensive treatment is often needed in certain patients with mixed dyslipidemia to help reach targets for all three key lipids," said Eli Roth, from the USA's University of Cincinnati College of Medicine. "The results from this study are encouraging because Trilipix combined with the lowest available dose of Crestor improved LDL, HDL and triglycerides," he added.
Trilipix is the first and only fibrate to be approved for use in combination with a statin. In certain patients, treatment guidelines recommend the combination of a fibrate with a statin to improve lipid levels, Abbott noted.
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