BioVex, a privately-held US biotechnology company, says that the UK Medicines and Healthcare Products Regulatory Agency (MHRA) has accepted its clinical trial application to conduct a Phase I study testing the safety and immunogenicity of its lead product, the infectious candidate vaccine for genital herpes, ImmunoVEX HSV2.
Preclinical studies suggest that the product prevented all symptoms of genital herpes and also triggered a strong immune response. ImmunoVEX HSV2 is a novel, live attenuated vaccine that has been designed to remove the genes that enable the herpes virus to avoid immune system detection. By removing the virus' ability to hide itself, the immune response is able to first recognize and then mount a response against the virus.
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