Vanda article praises firm's lipid-lowerer

Vanda Pharmaceuticals reports the publication of an article recommeding its drug candidate iloperidone in Schizophrenia Research, the official  journal of the Schizophrenia International Research Society,

The manuscript, entitled Common Effect of Antipsychotics on the  Biosynthesis and Regulation of Fatty Acids and Cholesterol Supports a  Key Role of Lipid Homeostasis in Schizophrenia, highlights the discovery  of a major effect of antipsychotics that the firm says sheds new light  on how the drugs work.

Vanda researchers analyzed the mechanism of action of 18 antipsychotics  at the molecular level and discovered that they regulate specific genes  that control the production and transport of lipids. These findings  suggest that antipsychotic drugs may alter the fluidity of cell  membranes of neurons, which could result in changes in neuronal  connectivity.