Viagra celebrates 10th global anniversary
Global drug giant Pfizer's Viagra (sildenafil citrate), a treatment which has transformed the lives of millions of men and their partners worldwide, celebrated its 10-year anniversary on March 27, 2008. Since receiving approval for the treatment of erectile dysfunction 10 years ago in the USA, the drug has been used by more than 35 million men in over 120 countries. In 1999 the word Viagra even made it into the Oxford English Dictionary.
The Pfizer scientists at Sandwich, UK, developed the first potent and selective inhibitor of an enzyme called PDE5 but the discovery of Viagra as a treatment for ED was somewhat accidental. The compound was initially trialled for the treatment of angina before some very notable side effects were reported and so the program was redirected towards ED.
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