Deficiency in vitamin D has been widely regarded as contributing to autoimmune disease, but an article in Autoimmunity Reviews explains that low levels of vitamin D may be a result, rather than a cause of disease and supplementing with vitamin D may actually exacerbate the illness.
The paper goes on to point out the form of vitamin D derived from food and supplements, 25-hydroxyvitamin D (25-D), is a secosteroid rather than a vitamin. Like corticosteroid medications, vitamin D may provide short-term relief by lowering inflammation but may exacerbate disease symptoms over the long term.
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