X4 Pharma falls as it reveals restructuring program

7 February 2025

Shares of rare disease drug developer X4 Pharmaceuticals (Nasdaq: XFOR) took a battering after it said it will restructure its workforce and capital spending.

The Boston, USA-based company now aims to focus efforts on advancing mavorixafor to treat those with chronic neutropenia, while also optimizing its US promotion of the drug, approved under the trade name Xolremdi for the treatment of WHIM syndrome (warts, hypogammaglobulinemia, infections and myelokathexis), a rare immunodeficiency.

X4 shares closed down 10.8% on Thursday and were down a further 6.9% at $0.51 in pre-market activity today.

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