Xoma has announced that based on a preliminary analysis of its ongoing 1,700-patient Phase III trial of E5, an antiendotoxin antibody, the company plans to continue developing the drug for Gram-negative sepsis. The trial is being conducted by Pfizer, Xoma's US marketing partner for the product. The news comes as a welcome boost in what has been a long and difficult development of E5 which, like other sepsis drugs, has suffered setbacks in the past (Marketletters passim).
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