Avir Green Hills starts next-gen flu spray Ph I

20 May 2007

Avir Green Hills Biotechnology, based in Vienna, Austria, has started the first clinical Phase I study for its novel influenza vaccine FLUVACC, which is based on the deletion of the NS1 gene. This week, the first eight volunteers were vaccinated in collaboration with the Medical University Vienna at the General Hospital. The protection rate is expected to surpass the rate achieved with currently available vaccines. With this step, Avir Green Hills says it has accomplished an important milestone in the development of more effective influenza vaccines based on a novel mechanism.

FLUVACC differs from a conventional influenza vaccine in three major characteristics and in the method of production, says the firm, explaining that it is administered as an intranasal spray and promises better and broader protection than currently-available vaccines.

The delNS technology is based on the deletion of the pathogenicity factor NS1. The resulting vaccine strain still looks like a pathogenic influenza virus to the body but is unable to cause disease. As a result, FLUVACC stimulates a strong immune response, which protects against influenza, says the Austrian firm.

This article is accessible to registered users, to continue reading please register for free.  A free trial will give you access to exclusive features, interviews, round-ups and commentary from the sharpest minds in the pharmaceutical and biotechnology space for a week. If you are already a registered user please login. If your trial has come to an end, you can subscribe here.

Login to your account

Become a subscriber

 

£820

Or £77 per month

Subscribe Now
  • Unfettered access to industry-leading news, commentary and analysis in pharma and biotech.
  • Updates from clinical trials, conferences, M&A, licensing, financing, regulation, patents & legal, executive appointments, commercial strategy and financial results.
  • Daily roundup of key events in pharma and biotech.
  • Monthly in-depth briefings on Boardroom appointments and M&A news.
  • Choose from a cost-effective annual package or a flexible monthly subscription
The Pharma Letter is an extremely useful and valuable Life Sciences service that brings together a daily update on performance people and products. It’s part of the key information for keeping me informed

Chairman, Sanofi Aventis UK





Today's issue

Company Spotlight