US firms AngioGenex and BioCheck have entered into an agreement to develop cancer diagnostic and prognostic products based on the Id-gene platform technology licensed exclusively to AGx by the Albert Einstein College of Medicine and the Memorial Sloan Kettering Cancer Center.
BioCheck and AGx, both privately-held companies, will apply their resources and expertise to develop diagnostics for early detection and prognosis of cancer based on the measurement of Id-proteins in blood and tumor tissue. A recently-approved Phase I SBIR grant will provide seed funding for the collaboration.
Partial loss of Id function leads to a profound resistance to the growth and metastasis of tumors in animals due to an inability to develop a supporting network of blood vessels (angiogenesis). In adults, the presence of Id proteins is associated with the formation of tumors.
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