Canadian biopharmaceutical company Bioniche Life Sciences says that intraperitoneal administration of its mycobacterial cell-wall DNA complex (MCC), stimulates increased anticancer activity in rat models of colon cancer. Specifically, the compound showed dose-dependant efficacy against both micro- and macrometastases in the peritoneal cavity of rodents with carcinomatosis.
The findings, which were presented at the annual meeting of the American Association of Cancer Research, were derived from a study conducted in collaboration with French firm Oncodesign Biotechnology.
Bioniche added that it is currently examining the drug, to be marketed under the brand name Urocidin, in a Phase III study as a therapy for non muscle-invasive bladder cancer.
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