US firm Chelsea Therapeutics says that it has entered into an exclusive license agreement with Japan's Dainippon Sumitomo Pharma, which entitles it to global development and commercialization rights to L-Threo DOPS (L-DOPS or droxidopa), outside Japan, Korea, China and Taiwan. The drug, which is a synthetic amino acid used in the treatment of neurogenic orthostatic hypotension, currently generates $50.0 million in annual revenue in Japan. The deal also allows Chelsea access to DSP's trial data, which the Charlotte-headquartered firm plans to submit to US and European Union regulatory authorities to expedite approval.
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