Emisphere starts Ph I oral heparin testing
Tarrytown, USA-based Emisphere Technologies has commenced clinicaltesting of oral heparin tablets utilizing its delivery agent, sodium N-[10(3 hydroxybenzoyl)decanoate. SNAD is Emisphere's drug delivery agent developed for use with the company's oral heparin tablets.
Emisphere plans to use SNAD as a delivery agent with formulations of both unfractionated heparin (UFH) and low molecular-weight heparin. The Phase I studies in the USA will initially look at escalating dosages of SNAD in combination with UFH in a tablet formulation to determine safety profiles.
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