Bristol, UK-based Hunter-Fleming has enrolled the first patients into a Phase IIa biomarker study investigating the use of HF0220 in mild-to-moderate Alzheimer's disease. The drug's novel mode of action enables a completely new approach to the treatment of inflammatory degenerative disorders such as AD, according to the firm.
HF0220 is regarded by the company as a major breakthrough and is currently being investigated for the treatment of a number of different conditions with significant unmet medical need. The Phase IIa multicenter, double-blind, placebo controlled, 40-patient, biomarker trial is designed to meet the following objectives: to demonstrate the safety and tolerability of HF0220, to determine an optimal dose for Phase IIb studies, and to elucidate further the novel mode of action.
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