EntreMed initiates Ph II trial with Panzem
EntreMed, a US clinical-stage pharmaceutical company focused on cancer and inflammatory diseases, has commenced a multicenter Phase II clinical trial with its drug candidate, Panzem NCD (2-methoxyestradiol), in patients with recurrent or resistant epithelial ovarian cancer.
The primary objective of this single-agent Phase II study will be to assess safety, pharmacokinetics, tumor response rate and progression-free survival with orally-administered Panzem NCD. EntreMed noted that the drug has US orphan drug designation for this indication.
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