Flamel Technologies SA of France has reported new clinical data whichshow that its microencapsulated aspirin product Asacard causes significantly less gastrointestinal damage than conventional coated aspirin. The company is developing its product for cardiovascular applications, in which patients are often on aspirin therapy for life.
70% fewer gastric lesions were seen in patients on Asacard 325mg compared to those on the same dose of coated aspirin (1.57 per patient versus 5.48 measured by endoscopy; p<0.001). Asacard is more tolerable because it inhibits thromboxane B2 while sparing prostacyclin, notes Flamel.
Flamel licenses Asacard to Searle in most European countries, and notes that the product is under registration in the UK. It is also in Phase I trials in the USA.
This article is accessible to registered users, to continue reading please register for free. A free trial will give you access to exclusive features, interviews, round-ups and commentary from the sharpest minds in the pharmaceutical and biotechnology space for a week. If you are already a registered user please login. If your trial has come to an end, you can subscribe here.
Login to your accountTry before you buy
7 day trial access
Become a subscriber
Or £77 per month
The Pharma Letter is an extremely useful and valuable Life Sciences service that brings together a daily update on performance people and products. It’s part of the key information for keeping me informed
Chairman, Sanofi Aventis UK
Copyright © The Pharma Letter 2025 | Headless Content Management with Blaze