ImmunoGen Drops Oncolysin B
The US biopharmaceutical company ImmunoGen has decided to discontinuethe development of Oncolysin B (anti-B4 blocked ricin), for the treatment of lymphoma after autologous bone marrow transplantation, following poor data from a Phase III trial.
The trial, which was funded by the US National Cancer Institute, involved 155 lymphoma patients. Preliminary data indicated that Oncolysin B offered no treatment advantage when compared to control.
The company says that it does not have the resources to continue development of a drug which has produced "ambiguous results," but may seek to outlicense or form a collaborative venture for the product at some point in the future.
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