Polyplus-transfection, a French company specializing in reagents for transfection and RNA interference, has produced the first batch of its transfection reagent in vivo-jetPEI, which it noted is made in full compliance with Good Manufacturing Practices.
The firm carried out preliminary work to transfer production to GMP-compliance in 2007 thanks to financial support from the AFM, France's Muscular Dystrophy Association. This has made it possible for a Phase II clinical trial to start in the field of cancer therapy this year using the GMP-compliant agent. Details of the clinical trial have not yet been disclosed. Polyplus-transfection offers its customers the possibility of using the same reagent from the early stages of preclinical research to clinical trials in humans, the firm noted.
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