The USA's WaferGen Biosystems presented positive data on the company's SmartChip Real-Time Polymerase Chain Reaction System alpha testing program, at the Cambridge Healthcare Institute's International Molecular Medicine Tri-Conference, held in San Francisco.
WaferGen reported key findings, including: the system's ability to generate real-time PCR results in clinical samples for approximately 1,000 oncology genes in triplicate on a single chip, using small amounts of RNA in less than three hours; a significant reduction in required reaction volume from 25-50uL to 100nl, saving significantly on reagent cost; establishment of the SmartChip system's equivalence in performance to current real-time PCR standards; demonstration of key SmartChip system workflow elements, including primer-ready SmartChips and the drying and reconstitution of primers for rapid high-throughput 100nL real-time PCR.
It is important to note that all of these results were achieved using clinical biological samples from emphysema, idiopathic pulmonary fibrosis and healthy patients, the company notes.
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