Atlanta, USA-based Sciele Pharma, a subsidiary of Japan's Shionogi, says that partner Addrenex Pharmaceuticals has initiated a Phase II clinical trial with ADX415 for the treatment of hypertension. This is a multicenter, double-blind, randomized, placebo-controlled, dose-ranging study that will involve 80 patients. ADX415 is a novel, patented, centrally-acting, alpha-adrenergic receptor agonist, specific to alpha-2 receptors.
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