Fluvastatin Slows CAD Development; LCAS
Sandoz' HMG-CoA reductase inhibitor Lescol (fluvastatin) can regress or slow progression of atherosclerosis in patients with coronary artery disease and mild-to-moderate low-density lipoprotein cholesterol elevations, according to angiographic results from the Lipoprotein and Coronary Atherosclerosis Study.
Fluvastatin patients exhibited significantly less progression than placebo; minimum lumen diameter decreased only 0.028mm versus 0.100mm, respectively. Regression of atherosclerosis occurred in 14.6% of the fluvastatin group and 8.3% of the placebo group.
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