Lilly Unveils New Glycopeptides
The recent upsurge in vancomycin-resistant enterococci has encouraged the search for new agents to treat these infections. Eli Lilly says it has developed a series of glycopeptide drugs from a parent compound (LY264826), which have the unusual property of being bactericidal against enterococci.
These derivatives are active against resistant enterococci strains, as well as a broad range of other Gram positive organisms including resistant strains of staphylococci and pneumococci. They were developed as part of an extensive screening program at Lilly.
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