Novartis expands Tekturna cardio-renal outcomes study
Swiss biotechnology firm Speedel says that its collaborator Novartis is set to expand the clinical trial program of SPP100 (aliskiren; Rasilez/Tekturna) to study organ protection potential beyond the already shown powerful reduction of blood pressure. The long-term ASPIRE HIGHER study, now forms the largest and most far-reaching cardio-renal outcomes program worldwide.
The two new studies are to evaluate the organ protection potential of the first-in-class direct renin inhibitor SPP100 for the treatment of heart failure and prevention of cardiovascular disease in the elderly, a patient segment that is predicted to more than double between 2000 and 2030. A third trial already underway is studying cardio-renal outcomes in diabetes.
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