USA-based Pro-Pharmaceuticals says that a review of data from Phase I and II trials show that no mucositis serious adverse events were found in patients treated with Davanat (mannose and galactose) and chemotherapy that included fluorouracil.
With most cancer treatment, about 5% to 15% of patients get mucositis, however, with 5-FU up to 40% contract mucositis and 10% to 15% get grade 3-4 oral mucositis. Yet, even in subjects with more than 100 cycles of treatments with Davanat and 5-FU, none experienced gastrointestinal SAEs.
"The data from the cancer patients in our clinical trials indicates Davanat improves efficacy and reduces the side effects associated with chemotherapy regimens," said chief executive Theodore Zucconi.
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