XTL discontinues HCV drug at Ph I
Israeli drugmaker XTL Biopharmaceuticals has terminated the development of XTL-2125, its investigational treatment for chronic hepatitis C virus infection, because HCV-RNA viral load reductions in a recent Phase I trial among XTL-2125 patients were not significantly different from those observed in the placebo group.
XTL chief executive Ron Bentsur said that "the completion of this Phase I trial concludes our research on the XTL legacy compounds that we inherited." He noted that bicifadine is the firm's lead product, in late-stage clinical development, and the company continues to explore the XTL-DOS program, "which is emerging as a very promising program in hepatitis C."
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