The USA's Cogentus Pharmaceuticals has enrolled the first patient in a pivotal Phase III study of its novel combination medicine CGT-2168. The trial will evaluate the antiplatelet therapy, which is a combination of clopidogrel (currently marketed by Bristol-Myers Squibb and Sanofi-Aventis as Plavix) and the gastroprotectant omeprazole in a single pill. The agent is designed to provide protective cardiovascular benefits while reducing the potentially-serious gastrointestinal side effects commonly associated with dual antiplatelet therapy, Cogentus noted.
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