Gilead's Preveon, Expanded Access

11 December 1997

Under an expanded-access program, Gilead Sciences is to donate itsexperimental AIDS vaccine, Preveon (adefovir dipivoxil), to HIV-positive patients aged over 13 who have failed treatment with at least two nucleoside analogs and one protease inhibitor. Patients must also fall within a certain range of low CD4 cell counts and have a high viral load. The vaccine is currently in the final stages of Phase III clinical trials, the company has said, noting that it plans to file a New Drug Application for the product in the second half of 1998.

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