Merck KGaA's colorectal cancer drug is set to propel Australian health authorities headlong into a new era of personalized medicine, in which the results of genetic testing determine which patients have access to the therapy, reports the Sidney Herald Tribune.
The drug, Erbitux (cetuximab), has no chance of working in 40% of bowel cancer patients. Their tumors feature a gene mutation that prevents the molecule from blocking its target cancer growth pathway, the newspaper explains.
However, for the other 60% whose cancer has the ''wild type'' version of the KRAS gene it offers a decent if usually temporary chance of slowing the cancer. For some it can even shrink tumors enough to make them amenable to surgery - holding out a modest prospect of a cure.
This article is accessible to registered users, to continue reading please register for free. A free trial will give you access to exclusive features, interviews, round-ups and commentary from the sharpest minds in the pharmaceutical and biotechnology space for a week. If you are already a registered user please login. If your trial has come to an end, you can subscribe here.
Login to your accountTry before you buy
7 day trial access
Become a subscriber
Or £77 per month
The Pharma Letter is an extremely useful and valuable Life Sciences service that brings together a daily update on performance people and products. It’s part of the key information for keeping me informed
Chairman, Sanofi Aventis UK
Copyright © The Pharma Letter 2025 | Headless Content Management with Blaze