Sangamo's ZFN-binding drug blocks HIV infection in harvested T-cells
California, USA-based Sangamo BioSciences, a developer of gene therapeutics, says that its developmental zinc-finger DNA-binding protein protects human T-cells from HIV infection. The firm explained that its ZFP nuclease technology can make T-cells resistant to HIV by altering the DNA sequence encoding the CCR5 cell-surface protein, which is an essential co-receptor for viral entry.
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