Vectibix: biomarker-specific benefits in mCRC
US biotechnology major Amgen says the results of a biomarker analysis indicate that, in metastatic colorectal cancer patients who have failed all other chemotherapeutic regimens, the efficacy of Vectibix (panitumumab) is confined to patients with non-mutated KRAS tumors. Specifically, in subjects with these tumors, the agent significantly increased progression-free survival and had an impact on quality of life and disease-related symptoms, compared to best supportive care alone.
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