Side effects may be good in breast cancer

10 November 2008

Women who experience side effects, such as hot flushes, night sweats and joint pain, when taking the breast cancer treatments tamoxifen or Anglo-Swedish drug major AstraZeneca's Arimidex (anastrozole), are less likely to have a recurrence of the disease, according to a study published in The Lancet Oncology.

The findings of the ATAC trial of 4,000 women suggest that the 37.5% of women taking the medications who experience hot flushes and night sweats after three months of treatment had 10% less chance of disease recurrence. Subjects who experienced joint pain had an even greater chance of the therapy being successful.

The article noted that the likely cause of the effect was that the treatments kill tumors by starving them of estrogen, and a lack of estrogen is known to cause the side effects.

This article is accessible to registered users, to continue reading please register for free.  A free trial will give you access to exclusive features, interviews, round-ups and commentary from the sharpest minds in the pharmaceutical and biotechnology space for a week. If you are already a registered user please login. If your trial has come to an end, you can subscribe here.

Login to your account

Become a subscriber

 

£820

Or £77 per month

Subscribe Now
  • Unfettered access to industry-leading news, commentary and analysis in pharma and biotech.
  • Updates from clinical trials, conferences, M&A, licensing, financing, regulation, patents & legal, executive appointments, commercial strategy and financial results.
  • Daily roundup of key events in pharma and biotech.
  • Monthly in-depth briefings on Boardroom appointments and M&A news.
  • Choose from a cost-effective annual package or a flexible monthly subscription
The Pharma Letter is an extremely useful and valuable Life Sciences service that brings together a daily update on performance people and products. It’s part of the key information for keeping me informed

Chairman, Sanofi Aventis UK



Company News Directory

Companies featured in this story

More ones to watch >


Today's issue

Company Spotlight