The US subsidiary of Japan's largest drugmaker, Takeda Pharmaceuticals North America, says that Kapidex (dexlansoprazole) delayed-release capsules are now available in pharmacies across the USA. Available in 30mg and 60mg doses, the drug was recently approved by the Food and Drug Administration for the treatment of heartburn associated with symptomatic non-erosive gastroesophageal reflux disease, the healing of erosive esophagitis and the maintenance of healed EE.
The company claims that Kapidex is the first proton pump inhibitor with a Dual Delayed Release formulation designed to provide two separate releases of medication. PPIs work by turning off many of the acid pumps in the stomach. The Takeda drug contains two types of enteric-coated granules resulting in a concentration-time profile with two distinct peaks: the first occurs one to two hours after administration, followed by a second within four to five hours. In addition, the product can be taken regardless of when food is consumed.
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