US drug major Merck & Co's Cancidas (caspofungin acetate) demonstrated a safety and efficacy profile generally similar to Gilead Sciences' antifungal agent AmBisome (liposomal amphotericin B for injection) in a clinical study involving its investigational use for pediatric empirical therapy against suspected invasive fungal infections in patients aged two to 17 years with persistent fever and neutropenia. AmBisome is regarded as a standard treatment option against IFI, Merck noted, adding that Cancidas in pediatric patients is investigational.
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